Your GLP-1 Stomach Problems Aren’t “Just Side Effects.” A Gastroenterologist Reveals the Upstream Protocol That’s Giving Women Their Digestion Back—Without Touching Their Dose.
The constipation, the sulfur burps, the cement-in-your-stomach feeling—none of it has to be the price you pay for losing weight. Here’s why everything you’ve been told to try was aimed at the wrong organ.
Women on Ozempic, Wegovy, and Mounjaro should be celebrating. Instead, they’re sitting in my office trying not to cry.
If you haven’t had a real bowel movement in over a week… if sulfur burps are ruining meals, car rides, and time with your grandkids… if your stomach feels like you swallowed concrete after every meal… and your doctor told you to drink water and try Miralax…
I need you to know something.
I’m Dr. Rebecca Marsh, a board-certified gastroenterologist with 14 years of practice focused on motility disorders. In the last three years, I’ve treated over 2,000 women on GLP-1 medications. And I’m watching the same thing happen to nearly every one of them.
They come in with a medicine cabinet full of laxatives. They’ve done everything their prescribing doctor suggested. Nothing is working. And most of them say some version of the same sentence:
“But I’ve lost the weight. So I just deal with it.”
They shouldn’t have to.
Every Laxative You’ve Tried Was Aimed at the Wrong Organ
Your GLP-1 medication slows your stomach. That’s how it helps with weight loss. But here’s what your prescribing doctor probably didn’t explain: the constipation, the sulfur gas, and the bloating aren’t three separate side effects. They’re one problem compounding itself.
When the stomach slows, food ferments. Fermentation produces sulfur gas. The gas stretches the stomach. The stretched stomach slows further. It’s a feedback loop—and every day you don’t break it, it digs in deeper.
Miralax can’t touch it. Neither can Colace, Dulcolax, or mag citrate. They all work downstream in the colon. None of them reach your stomach—which is where the problem actually lives.
The Three-Pathway Protocol That’s Changing Everything
Once the feedback loop was clear, the solution was obvious. You don’t break a cycle by treating the end of it. You address all three pathways at the source, at the same time. That’s the protocol I now recommend to every GLP-1 patient who walks through my door. And a company called Motilli built the exact formula into a daily gummy.
Wake up the stomach.
Celery juice concentrate contains apigenin, which targets the vagus nerve signal your GLP-1 medication quieted down. Think of it as restarting the rhythm that got slowed.
Kill the sulfur.
Chlorophyllin binds directly to hydrogen sulfide—the specific compound behind those rotten-egg burps—and neutralizes it before it rises. Most patients tell me the burps start fading in the first week.
Soften what’s stuck.
Soluble prebiotic fiber does what every doctor should have specified instead of just saying “eat more fiber.” It softens and lubricates without adding bulk. Insoluble fiber in a backed-up system is like adding more cars to a traffic jam.
“Three pathways. One gummy. All working on the organ that every laxative in your cabinet ignores.”
What I’m Hearing From Patients—Over and Over Again
I’ve tracked this protocol across over 2,000 women. The pattern is remarkably consistent.
Within the first week, the sulfur burps start fading. One patient told me she ate garlic bread at a restaurant for the first time in four months and didn’t spend the rest of the night apologizing to her husband.
By weeks two and three, the cement feeling starts lifting. Women tell me they wake up and realize their stomach feels… normal. Not empty. Not bloated. Just normal. Several said they forgot what that felt like. Bowel movements start coming back—not forced, not urgent, just happening the way they’re supposed to.
By week six, the feedback loop is broken. The stomach moves again, so fermentation drops, so gas drops, so distension drops, so the stomach moves even better. The same cycle that was destroying their digestion starts running in reverse. They stop planning around their symptoms. They stop tracking. They just live.
One husband told his wife she seemed “lighter”—not in weight, in mood. A patient’s daughter called my office to say thank you because her mom came to Thanksgiving dinner for the first time in two years without leaving the table early.
My own mother started Mounjaro eight months ago. Lost 22 pounds. Developed every symptom I just described. I put her on the same protocol. She texts me every Sunday now—not about her stomach. About what she cooked for dinner. That silence is the result.
Why Waiting Makes It Harder
Every month the feedback loop continues, the gastric slowdown digs in deeper. I’ve seen women who caught this at month two bounce back in weeks. I’ve seen women who waited a year need three times as long.
Motilli offers a 90-day money-back guarantee. Use it for the full three months. If your digestion doesn’t come back, you get every cent back.
“Your GLP-1 prescription should have included a plan for your stomach. It didn’t. Now it can.”
Try Motilli Risk-Free for 90 Days
Three pathways. One gummy. Wake up the stomach. Kill the sulfur. Soften what’s stuck. All working upstream where your laxatives can’t reach.
90-Day Money-Back Guarantee.
No dose changes. No prescriptions. Just results.
Motilli is a dietary supplement. It is not intended to diagnose, treat, cure, or prevent any disease. Consult your doctor before starting any new supplement, especially if you are on GLP-1 medications.